Ingham Philip
MRC Intercellular Signalling Group, Centre for Developmental Genetics, School of Medicine and Biomedical Science, University of Sheffield, Sheffield S10 2TN, UK.
Curr Biol. 2003 Aug 5;13(15):R583-4. doi: 10.1016/s0960-9822(03)00516-5.
Philip Ingham grew up in Liverpool and graduated from Cambridge University in 1977. He did his D. Phil in Developmental Genetics at Sussex University and postdoctoral work in Strasbourg, France before joining the laboratory of David Ish-Horowicz at the ICRF Mill Hill Laboratories. Here he applied the emerging technique of tissue in situ hybridisation to the analysis of the Drosophila segmentation genes. After a short spell at the MRC Laboratory of Molecular Biology in Cambridge, he rejoined the ICRF as a Research Scientist at the Developmental Biology Unit in Oxford. His group pioneered the analysis of the Hedgehog signalling pathway in Drosophila and in collaboration with the labs of Andy McMahon and Cliff Tabin at Harvard University, discovered the Hedgehog gene family in vertebrates. In 1996 he was appointed Professor of Developmental Genetics at the University of Sheffield where he has established the Centre for Developmental Genetics.
菲利普·英厄姆在利物浦长大，1977年毕业于剑桥大学。他在萨塞克斯大学完成了发育遗传学的博士学位，并在法国斯特拉斯堡做了博士后研究，之后加入了ICRF米尔希尔实验室大卫·伊什-霍罗维茨的实验室。在这里，他将新兴的组织原位杂交技术应用于果蝇体节基因的分析。在剑桥的MRC分子生物学实验室短暂工作后，他回到ICRF，成为牛津发育生物学部门的一名研究科学家。他的团队率先在果蝇中分析了刺猬信号通路，并与哈佛大学安迪·麦克马洪和克里夫·塔宾的实验室合作，在脊椎动物中发现了刺猬基因家族。1996年，他被任命为谢菲尔德大学发育遗传学教授，并在那里建立了发育遗传学中心。
