• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

SLControl:用于肌肉力学的基于个人计算机的数据采集与分析

SLControl: PC-based data acquisition and analysis for muscle mechanics.

作者信息

Campbell Kenneth S, Moss Richard L

机构信息

Department of Physiology, University of Wisconsin-Madison, 53706, USA.

出版信息

Am J Physiol Heart Circ Physiol. 2003 Dec;285(6):H2857-64. doi: 10.1152/ajpheart.00295.2003. Epub 2003 Aug 7.

DOI:10.1152/ajpheart.00295.2003
PMID:12907419
Abstract

SLControl is a computerized data acquisition and analysis system that was developed in our laboratory to help perform mechanical experiments using striated muscle preparations. It consists of a computer program (Windows 2000 or later) and a commercially available data acquisition board (16-bit resolution, DAP5216a, Microstar Laboratories, Bellevue, WA). Signals from the user's existing equipment representing force, fiber length (FL), and (if desired) sarcomere length (SL) are connected to the system through standard Bayonet Neill Concelman cables and saved to data files for later analysis. Output signals from the board control FL and trigger additional equipment, e.g., flash lamps. Windows dialogs drive several different experimental protocols, including slack tests and rate of tension recovery measurements. Precise measurements of muscle stiffness and force velocity/power characteristics can also be accomplished using SL and tension control, respectively. In these situations, the FL command signal is updated in real time (at rates > or =2.5 kHz) in response to changes in the measured SL or force signals. Data files can be exported as raw text or analyzed within SLControl with the use of built-in tools for cursor analysis, digital filtering, curve fitting, etc. The software is available for free download at http://www.slcontrol.com.

摘要

SLControl是我们实验室开发的一种计算机化数据采集与分析系统,用于辅助进行使用横纹肌标本的力学实验。它由一个计算机程序(Windows 2000或更高版本)和一块市售数据采集板(16位分辨率,DAP5216a,Microstar Laboratories,华盛顿州贝尔维尤)组成。来自用户现有设备的代表力、纤维长度(FL)以及(如有需要)肌节长度(SL)的信号,通过标准的卡口尼尔-康塞尔曼电缆连接到系统,并保存到数据文件中以供后续分析。采集板的输出信号控制纤维长度并触发其他设备,例如闪光灯。Windows对话框驱动几种不同的实验方案,包括松弛测试和张力恢复速率测量。肌肉刚度以及力-速度/功率特性的精确测量也可分别使用肌节长度和张力控制来完成。在这些情况下,纤维长度命令信号会根据测得的肌节长度或力信号的变化实时更新(更新速率≥2.5 kHz)。数据文件可以导出为原始文本格式,或者使用内置的光标分析、数字滤波、曲线拟合等工具在SLControl中进行分析。该软件可从http://www.slcontrol.com免费下载。

相似文献

1
SLControl: PC-based data acquisition and analysis for muscle mechanics.SLControl:用于肌肉力学的基于个人计算机的数据采集与分析
Am J Physiol Heart Circ Physiol. 2003 Dec;285(6):H2857-64. doi: 10.1152/ajpheart.00295.2003. Epub 2003 Aug 7.
2
Instantaneous force-velocity-length relationship in diaphragmatic sarcomere.
J Appl Physiol (1985). 1997 Feb;82(2):404-12. doi: 10.1152/jappl.1997.82.2.404.
3
MyoRobot 2.0: An advanced biomechatronics platform for automated, environmentally controlled skeletal muscle single fiber biomechanics assessment employing inbuilt real-time optical imaging.MyoRobot 2.0:一种先进的生物机电一体化平台,用于采用内置实时光学成像的自动化、环境控制的骨骼肌单纤维生物力学评估。
Biosens Bioelectron. 2019 Aug 1;138:111284. doi: 10.1016/j.bios.2019.04.052. Epub 2019 May 12.
4
A non-cross-bridge stiffness in activated frog muscle fibers.激活的青蛙肌肉纤维中的非横桥僵硬度。
Biophys J. 2002 Jun;82(6):3118-27. doi: 10.1016/S0006-3495(02)75653-1.
5
Sarcomere mechanics in striated muscles: from molecules to sarcomeres to cells.横纹肌中的肌节力学:从分子到肌节再到细胞。
Am J Physiol Cell Physiol. 2017 Aug 1;313(2):C134-C145. doi: 10.1152/ajpcell.00050.2017. Epub 2017 May 24.
6
Potential errors in fiber length measurements resulting from lever arm rotation during mechanical testing of muscle cells.在对肌肉细胞进行机械测试时,由于杠杆臂旋转而导致纤维长度测量可能出现的误差。
J Biomech. 2011 Jun 3;44(9):1797-800. doi: 10.1016/j.jbiomech.2011.03.027. Epub 2011 Apr 8.
7
Heterogeneity of mean sarcomere length in different fibres: effects on length range of active force production in rat muscle.不同肌纤维中平均肌节长度的异质性:对大鼠肌肉主动力产生长度范围的影响。
Eur J Appl Physiol Occup Physiol. 1994;68(6):489-96. doi: 10.1007/BF00599518.
8
Contractile properties of mouse single muscle fibers, a comparison with amphibian muscle fibers.小鼠单根肌纤维的收缩特性,与两栖类肌纤维的比较。
J Exp Biol. 2005 May;208(Pt 10):1905-13. doi: 10.1242/jeb.01573.
9
Force-length properties in stable skeletal muscle fibers--theoretical considerations.稳定骨骼肌纤维中的力-长度特性——理论思考
J Biomech. 1996 Sep;29(9):1235-40. doi: 10.1016/0021-9290(96)00013-9.
10
Detachment of low-force bridges contributes to the rapid tension transients of skinned rabbit skeletal muscle fibres.低力桥的分离有助于去皮肤的兔骨骼肌纤维的快速张力瞬变。
J Physiol. 1997 May 15;501 ( Pt 1)(Pt 1):149-64. doi: 10.1111/j.1469-7793.1997.149bo.x.

引用本文的文献

1
Intraoperative phrenic nerve stimulation to prevent diaphragm fiber weakness during thoracic surgery.术中膈神经刺激以预防胸外科手术期间膈肌纤维无力。
PLoS One. 2025 Apr 1;20(4):e0320936. doi: 10.1371/journal.pone.0320936. eCollection 2025.
2
Differential effects of myosin activators on myocardial contractile function in nonfailing and failing human hearts.肌球蛋白激活剂对非衰竭和衰竭人类心脏心肌收缩功能的不同影响。
Am J Physiol Heart Circ Physiol. 2025 Jan 1;328(1):H161-H173. doi: 10.1152/ajpheart.00252.2024. Epub 2024 Oct 25.
3
Strain rate of stretch affects crossbridge detachment during relaxation of intact cardiac trabeculae.
牵张应变率影响完整心肌小梁松弛时的横桥解离。
PLoS One. 2024 Mar 4;19(3):e0297212. doi: 10.1371/journal.pone.0297212. eCollection 2024.
4
Prior Freezing Has Minimal Impact on the Contractile Properties of Permeabilized Human Myocardium.预先冷冻对人心肌通透化收缩性能的影响很小。
J Am Heart Assoc. 2022 May 17;11(10):e023010. doi: 10.1161/JAHA.121.023010. Epub 2022 May 10.
5
Reduced preload increases Mechanical Control (strain-rate dependence) of Relaxation by modifying myosin kinetics.减少前负荷通过改变肌球蛋白动力学增加弛豫的机械控制(应变率依赖性)。
Arch Biochem Biophys. 2021 Aug 15;707:108909. doi: 10.1016/j.abb.2021.108909. Epub 2021 May 18.
6
cMyBPC phosphorylation modulates the effect of omecamtiv mecarbil on myocardial force generation.cMyBPC 磷酸化调节 omecamtiv mecarbil 对心肌收缩力的影响。
J Gen Physiol. 2021 Jul 5;153(7). doi: 10.1085/jgp.202012816.
7
Heart Failure in Humans Reduces Contractile Force in Myocardium From Both Ventricles.人类心力衰竭会降低两个心室心肌的收缩力。
JACC Basic Transl Sci. 2020 Jul 22;5(8):786-798. doi: 10.1016/j.jacbts.2020.05.014. eCollection 2020 Aug.
8
AAV9 gene transfer of cMyBPC N-terminal domains ameliorates cardiomyopathy in cMyBPC-deficient mice.AAV9 基因转导 cMyBPC N 端结构域改善了 cMyBPC 缺陷型小鼠的心肌病。
JCI Insight. 2020 Sep 3;5(17):130182. doi: 10.1172/jci.insight.130182.
9
Deletion of Enigma Homologue from the Z-disc slows tension development kinetics in mouse myocardium.Z 盘上 Enigma 同源物缺失会减缓小鼠心肌张力发展动力学。
J Gen Physiol. 2019 May 6;151(5):670-679. doi: 10.1085/jgp.201812214. Epub 2019 Jan 14.
10
The HCM-causing Y235S cMyBPC mutation accelerates contractile function by altering C1 domain structure.导致 HCM 的 Y235S cMyBPC 突变通过改变 C1 结构域结构加速收缩功能。
Biochim Biophys Acta Mol Basis Dis. 2019 Mar 1;1865(3):661-677. doi: 10.1016/j.bbadis.2019.01.007. Epub 2019 Jan 3.