Liu H M, Wang Y H, Chen Y F, Tu Y K, Huang K M
Department of Medical Imaging, National Taiwan University Hospital, 7 Chung-Shan South Road, 10016 Taipei, Taiwan.
Neuroradiology. 2003 Sep;45(9):644-9. doi: 10.1007/s00234-003-1055-4. Epub 2003 Aug 8.
Our purpose was to evaluate the safety and efficacy of endovascular treatment of brain-stem arteriovenous malformations (AVMs), reviewing six cases managed in the last 5 years. There were four patients who presented with bleeding, one with a progressive neurological deficit and one with obstructive hydrocephalus. Of the six patients, one showed 100%, one 90%, two 75% and two about 50% angiographic obliteration of the AVM after embolisation; the volume decreased about 75% on average. Five patients had a good outcome and one an acceptable outcome, with a mild postprocedure neurological deficit; none had further bleeding during midterm follow-up. Endovascular management of a brain-stem AVM may be an alternative to treatment such as radiosurgery and microsurgery in selected cases. It may be not as risky as previously thought. Embolisation can reduce the size of the AVM and possibly make it more treatable by radiosurgery and decrease the possibility of radiation injury.
我们的目的是评估脑干动静脉畸形(AVM)血管内治疗的安全性和有效性,回顾过去5年中治疗的6例病例。4例患者表现为出血,1例有进行性神经功能缺损,1例有梗阻性脑积水。6例患者中,1例在栓塞后AVM血管造影闭塞率达100%,1例为90%,2例为75%,2例约为50%;体积平均减少约75%。5例患者预后良好,1例预后尚可,术后有轻度神经功能缺损;中期随访期间均无再次出血。在某些病例中,脑干AVM的血管内治疗可能是放射外科和显微外科等治疗方法的替代方案。其风险可能没有之前认为的那么大。栓塞可以缩小AVM的大小,可能使其更适合放射外科治疗,并降低放射损伤的可能性。