Levinger Eliya, Segev Eitan, Geyer Orna
Carmel Medical Center, Haifa.
Harefuah. 2003 Jul;142(7):500-2, 568, 567.
To evaluate the effect of contact transscleral diode cyclophotocoagulation for refractory glaucoma.
Thirty-three patients with intractable glaucoma were treated with contact diode cyclophotocoagulation. Laser radiation (810-nm) was delivered to the eye by a fiberoptic (G-probe) placed 1.2 mm behind the limbus. Laser setting used was 2 W power for the duration of 2 seconds. Forty to 45 laser spots were applied over 360 degrees. Intraocular pressure (IOP), the number of glaucoma medications, visual acuity and complications were all assessed at last follow-up visit 12 months after laser treatment. Success was defined as IOP of less than 22 mmHg with medications at the last follow-up visit.
The mean IOP decreased from 37.8 +/- 8.0 mmHg pre-diode treatment to 18.2 +/- 9.2 mmHg at last follow-up visit after treatment (p < 0.05). About 73% of patients achieved IOP of between 2 and 22 mmHg at final follow-up. The mean number of medications required decreased from 3.4 +/- 1.1 before to 2.4 +/- 1 after treatment (p < 0.05). Fifty five percent of the patients had a deterioration in visual acuity. Other complications were few and included transient hyphema, uveitis, choroidal detachment and hypotony.
Contact transscleral diode cyclophotocoagulation is effective in lowering IOP and reducing the number of glaucoma medications in refractory glaucoma. The deterioration in visual acuity post-laser is a limitation of the treatment.
评估接触式经巩膜二极管睫状体光凝术治疗难治性青光眼的效果。
对33例难治性青光眼患者进行接触式二极管睫状体光凝术治疗。通过置于角膜缘后1.2 mm处的光纤(G探头)向眼内发射激光(810 nm)。使用的激光参数为功率2 W,持续时间2秒。在360度范围内施加40至45个激光点。在激光治疗后12个月的最后一次随访中评估眼压(IOP)、青光眼药物使用数量、视力和并发症情况。成功定义为最后一次随访时使用药物后眼压低于22 mmHg。
二极管治疗前平均眼压为37.8±8.0 mmHg,治疗后最后一次随访时降至18.2±9.2 mmHg(p<0.05)。约73%的患者在最终随访时眼压在2至22 mmHg之间。所需药物的平均数量从治疗前的3.4±1.1降至治疗后的2.4±1(p<0.05)。55%的患者视力下降。其他并发症较少,包括短暂性前房积血、葡萄膜炎、脉络膜脱离和低眼压。
接触式经巩膜二极管睫状体光凝术在降低难治性青光眼眼压和减少青光眼药物使用数量方面有效。激光治疗后视力下降是该治疗方法的一个局限性。