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腹膜间皮瘤的临床表现。

Clinical presentation of peritoneal mesothelioma.

作者信息

Acherman Yair I Z, Welch Laura S, Bromley Christina M, Sugarbaker Paul H

机构信息

The Washington Cancer Institute, Washington Hospital Center, DC 20010, USA.

出版信息

Tumori. 2003 May-Jun;89(3):269-73. doi: 10.1177/030089160308900307.

DOI:10.1177/030089160308900307
PMID:12908781
Abstract

AIM

To describe the clinical presentation of peritoneal mesothelioma and its impact on survival.

METHODS

Data was collected from 51 patients with peritoneal mesothelioma treated at the Washington Cancer Institute. The demographic, clinical and pathologic information were analyzed.

RESULTS

Pain was the most common symptom (recorded in 33% of patients); increased abdominal girth occurred in 31%, increased abdominal girth and pain in 5%, and a new onset hernia in 12%. In an additional 14% of patients, a variety of other clinical findings led to the diagnosis. There was a statistically significant difference in survival by gender, weight loss and volume of disease.

CONCLUSIONS

Pain was the most common initial presenting symptom, with increased abdominal girth as a second. A more favorable prognosis occurred in women with a small disease volume.

摘要

目的

描述腹膜间皮瘤的临床表现及其对生存的影响。

方法

收集了华盛顿癌症研究所治疗的51例腹膜间皮瘤患者的数据。对人口统计学、临床和病理信息进行了分析。

结果

疼痛是最常见的症状(33%的患者有记录);31%的患者出现腹围增加,5%的患者腹围增加且伴有疼痛,12%的患者出现新发疝气。另外14%的患者通过各种其他临床发现得以确诊。生存情况在性别、体重减轻和疾病体积方面存在统计学上的显著差异。

结论

疼痛是最常见的初始表现症状,腹围增加是第二常见症状。疾病体积小的女性预后更有利。

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