Normal range and variation of the zona pellucida-induced acrosome reaction in fertile men.
作者信息
Liu De Yi, Stewart Tanya, Baker H W Gordon
机构信息
Department of Obstetrics and Gynaecology, University of Melbourne, Carlton, Victoria.
出版信息
Fertil Steril. 2003 Aug;80(2):384-9. doi: 10.1016/s0015-0282(03)00603-4.
OBJECTIVE
To investigate the normal range of the zona pellucida (ZP)-induced acrosome reaction (AR) in fertile men.
DESIGN
A study of normative data.
SETTING
Academic research and teaching tertiary hospital.None.Fertile men (n = 111) who had children or whose female partner was currently pregnant. MAIN OUTCOME MEASURE (S): Semen analysis, sperm-ZP binding, and the ZP-induced AR.
RESULT(S): There was wide range for the ZP-induced AR: 20%-98% with a mean of 48%. The ZP-induced AR was significantly correlated with sperm concentration and normal morphology. The ZP-induced AR was significantly lower in men with sperm concentration <or=60 x 10(6)/mL than those with sperm concentration >60 x 10(6)/mL. Similarly, men with normal sperm morphology >or=15% had significantly higher ZP-induced AR than men with normal morphology <15%.
CONCLUSION(S): There is a wide range of the ZP-induced AR in fertile men that is correlated with sperm concentration and normal morphology.
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