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Bone marrow necrosis and human parvovirus associated infection preceding an Ph1+ acute lymphoblastic leukemia.

作者信息

Petrella T, Bailly F, Mugneret F, Caillot D, Chavanet P, Guy H, Solary E, Waldner A, Devilliers E, Carli P M

机构信息

Department of Pathology, Faculty of Medicine, Dijon, France.

出版信息

Leuk Lymphoma. 1992 Nov;8(4-5):415-9. doi: 10.3109/10428199209051023.

DOI:10.3109/10428199209051023
PMID:1290967
Abstract

A case of bone marrow necrosis associated with a serologically documented recent Parvovirus B 19 infection which preceded the development of PH1+ acute lymphoblastic leukemia is reported. No conclusions can be drawn on the basis of a single case but the question of the role of human Parvovirus B19 in the pathogenesis of bone marrow necrosis is discussed. It is suggested that the virus may act as a co-factor for the induction of bone marrow necrosis, in some cases.

摘要

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History of Parvovirus B19 infection is associated with a DNA methylation signature in childhood acute lymphoblastic leukemia.
parvovirus B19 感染史与儿童急性淋巴细胞白血病中的 DNA 甲基化特征有关。
Epigenetics. 2011 Dec;6(12):1436-43. doi: 10.4161/epi.6.12.18464.
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Association of acute parvovirus B19 infection with new onset of acute lymphoblastic and myeloblastic leukaemia.急性细小病毒B19感染与急性淋巴细胞白血病和急性髓细胞白血病新发病例的关联。
J Clin Pathol. 2003 Nov;56(11):873-5. doi: 10.1136/jcp.56.11.873.
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Human parvovirus B19.人细小病毒B19
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