Pierzchała W, Osławska-Dzierzega A
II Katedry i Kliniki Chorób Wewnetrznych Slaskiej Akademii Medycznej, Katowicach.
Pneumonol Alergol Pol. 1992;60(5-6):49-54.
The study was carried out on a group of 54 galenite miners (composed of PbS slats) (age 37.9 +/- 7.5 years). The following parameters were assessed: VC, TLC, RV, RV%TLC, FEV1, FEV1%VC, Raw, Gaw, FEF50%, FEF75%. Also the ventilatory homogeneous index was calculated V2:V1 basing on the analysis of the flow volume curve. The control consisted of subjects living in the vicinity of the mine and smelting works. In 3.1% of the miners various stages of increased flow obstruction was found. In 8.3% signs of emphysematous changes, in 23.9% minor disturbances of bronchial resistance. In comparison with the control the miners demonstrated expiratory flow mainly in the small airways. Duration of exposure and co-existent chronic bronchitis increased the above mentioned observations and decreased the homogeneity index.
该研究针对一组54名(由方铅矿板组成)的辉锑矿矿工(年龄37.9±7.5岁)展开。评估了以下参数:肺活量(VC)、肺总量(TLC)、残气量(RV)、残气量占肺总量百分比(RV%TLC)、第一秒用力呼气容积(FEV1)、第一秒用力呼气容积占肺活量百分比(FEV1%VC)、气道阻力(Raw)、比气道传导率(Gaw)、用力呼出50%肺活量时的瞬间流量(FEF50%)、用力呼出75%肺活量时的瞬间流量(FEF75%)。此外,基于流量-容积曲线分析计算了通气均匀指数V2:V1。对照组由居住在矿山和冶炼厂附近的人员组成。在3.1%的矿工中发现了不同阶段的气流阻塞增加。在8.3%的矿工中出现了肺气肿改变的迹象,在23.9%的矿工中存在支气管阻力的轻微紊乱。与对照组相比,矿工的呼气气流主要出现在小气道。暴露时间和并存的慢性支气管炎加剧了上述观察结果,并降低了均匀指数。