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[医疗处方计算机化对药物不良反应发生率的影响]

[Impact of medical prescription computerisation on the incidence of adverse drug effects].

作者信息

Maurer C, Lecointre K, Cachin N, Latawiec K, Ouadfel F, Lahmek P, Fauvelle F, Piquet J

机构信息

Service de Pneumologie, Centre Hospitalier Le Raincy-Montfermeil, Montfermeil.

出版信息

Rev Mal Respir. 2003 Jun;20(3 Pt 1):355-63.

PMID:12910110
Abstract

INTRODUCTION

Adverse drug effects are a significant public health problem. Prescription errors are responsible for a significant proportion of these adverse effects.

METHODS

We have aimed to improve the link between generation of and interpretation of a prescription through computerisation. The prescription sheet, which is generated daily, was organised to allow care planning without the need to re-copy out treatments on the sheet. A prescription aid was available which was based on a core group of drugs commonly used in our respiratory service. The aim of the study was to compare the various types of errors observed during 6 weeks of computerized prescriptions (229 files) to a retrospective series of handwritten prescriptions of the service at an identical time (184 files) the previous year. The case-mix was identical for both analysed periods.

RESULTS

The total number of technical prescribing errors in the 1,599 handwritten lines (49.27% error) was significantly higher (p<0.001) than the 1,805 computerized prescriptions lines (42.88% error). The errors of copying (p<0.001), eligibility (p<0.001) and incorrect spelling (p<0.05) were the main sources of error which were significantly reduced by computerisation.

CONCLUSION

Computerised prescription is likely to reduce the incidence of prescribing errors and adverse drug effects.

摘要

引言

药物不良反应是一个重大的公共卫生问题。处方错误在这些不良反应中占很大比例。

方法

我们旨在通过计算机化改善处方生成与解读之间的联系。每日生成的处方单经过整理,以便在无需重新抄写治疗信息的情况下进行护理规划。提供了一种基于我们呼吸科常用的一组核心药物的处方辅助工具。该研究的目的是将6周内计算机化处方(229份档案)中观察到的各类错误与上一年同期该科室手写处方的回顾性系列(184份档案)进行比较。两个分析时间段的病例组合相同。

结果

1599行手写处方中的技术处方错误总数(错误率49.27%)显著高于1805行计算机化处方中的错误总数(错误率42.88%)(p<0.001)。抄写错误(p<0.001)、适用性错误(p<0.001)和拼写错误(p<0.05)是主要的错误来源,计算机化显著减少了这些错误。

结论

计算机化处方可能会降低处方错误和药物不良反应的发生率。

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The effect of electronic prescribing on medication errors and adverse drug events: a systematic review.电子处方对用药错误和药物不良事件的影响:系统评价。
J Am Med Inform Assoc. 2008 Sep-Oct;15(5):585-600. doi: 10.1197/jamia.M2667. Epub 2008 Jun 25.