Amirat L, le Pimpec Barthes F, Danel C, Poulet B, Riquet M
Service de Chirurgie Thoracique, Hôpital Européen Georges Pompidou, Paris, France.
Rev Mal Respir. 2003 Jun;20(3 Pt 1):429-32.
Pulmonary tumours resembling the foetal lung are primitive tumours and are rare. They include pneumoblastomas and foetal-type pulmonary adenocarcinoma. Foetal-type adenocarcinomas (FTA) fall into two categories: well differentiated and poorly differentiated. Poorly-differentiated FTA, which tends to occur in older subjects who smoke and who are male, has a guarded prognosis and is classified as a variety of pulmonary adenocarcinoma.
Well-differentiated FTAs are also called endodermic tumours resembling the foetal lung. These are large tumours, peripherally sited but with endobronchial extension that occur primarily in younger patients who are often non-smoking females. They comprise of tubular glandular structures and morular metaplasia, compact and rounded cellular proliferation's which contain endocrine cells. We have described three cases.
These tumours are important to classify as their prognosis is good if surgical excision is complete.
类似胎儿肺的肺部肿瘤是原发性肿瘤,较为罕见。它们包括肺母细胞瘤和胎儿型肺腺癌。胎儿型腺癌(FTA)分为两类:高分化型和低分化型。低分化型FTA往往发生在吸烟的老年男性患者中,预后不佳,被归类为一种肺腺癌。
高分化型FTA也被称为类似胎儿肺的内胚层肿瘤。这些是大肿瘤,位于周边但有支气管内延伸,主要发生在年轻患者中,这些患者通常是非吸烟女性。它们由管状腺结构和桑椹样化生组成,是紧密且圆形的细胞增殖,其中含有内分泌细胞。我们描述了三例病例。
这些肿瘤的分类很重要,因为如果手术切除彻底,其预后良好。