Kurian M A, King M D
Department of Paediatric Neurology, The Children's Hospital, Dublin, Eire.
Neuropediatrics. 2003 Jun;34(3):152-5. doi: 10.1055/s-2003-41275.
A previously healthy one-year-old boy, the youngest child of unrelated parents, presented with a four-week history of episodes of myoclonus triggered only by tactile stimulation to his head. There had been no loss of developmental skills. The electroencephalogram (EEG) revealed generalised polyspike wave activity both with and without clinical correlate. The infant was started on sodium valproate, which resulted in cessation of the myoclonic episodes one week after starting therapy. At subsequent follow-up (at 18 months) the infant was seizure free and a repeat EEG was normal. This case of non-progressive reflex myoclonic epilepsy of infancy triggered only by head tapping (and not by acoustic stimuli) is an extremely rare phenomenon. Reflex myoclonic epilepsy of infancy represents a distinct subtype of myoclonic epilepsy in infancy. It should be considered as an age-dependent idiopathic generalised epileptic syndrome with an apparently good prognosis.
一名此前健康的一岁男童，是父母非近亲的最小孩子，出现了仅由头部触觉刺激引发的为期四周的肌阵挛发作史。其发育技能未丧失。脑电图（EEG）显示，无论有无临床相关性，均存在全身性多棘波活动。该婴儿开始服用丙戊酸钠，治疗一周后肌阵挛发作停止。在随后的随访（18个月时）中，婴儿无癫痫发作，复查脑电图正常。这种仅由轻拍头部（而非听觉刺激）引发的非进行性婴儿反射性肌阵挛癫痫病例极为罕见。婴儿反射性肌阵挛癫痫是婴儿肌阵挛癫痫的一种独特亚型。它应被视为一种年龄依赖性特发性全身性癫痫综合征，预后明显良好。
