Kobayashi Shigeto, Yano Tetsuro, Matsumoto Yoshifuji, Numano Fujio, Nakajima Nobuyuki, Yasuda Keishu, Yutani Chikao, Nakayama Toshiko, Tamakoshi Akiko, Kawamura Takashi, Ohno Yoshiyuki, Inaba Yutaka, Hashimoto Hiroshi
Juntendo University School of Medicine, Tokyo, Japan.
Arthritis Rheum. 2003 Aug 15;49(4):594-8. doi: 10.1002/art.11195.
To elucidate epidemiologic and clinical manifestations of Japanese patients with giant cell arteritis (GCA), the first nationwide survey for GCA was conducted in 1998 in Japan.
The first questionnaire on GCA for patients treated in 1997 was sent to 10,717 medical departments in Japan. A total of 177 patients were reported. Among the 177 patients, 66 GCA patients with detailed clinical and epidemiologic features on second survey were analyzed.
Prevalence in patients 50 years of age and older in 1997 was 1.47 per 100,000 population in Japan. The average age at onset was 71.5 years old. The male:female ratio was 1:1.7. The association with permanent and complete visual loss (6.5%), jaw claudication (15.2%), and polymyalgia rheumatica (PMR) (30.3%) were low in frequency compared with those reported from other countries. All patients were treated with corticosteroids. Only 3 (4.5%) patients were reported as deceased due to other causes.
The prevalence of GCA in Japan was revealed to be extremely low compared with other countries. Clinical findings of permanent and complete visual loss, jaw claudication, and PMR were infrequent among Japanese patients with GCA.
为阐明日本巨细胞动脉炎（GCA）患者的流行病学特征和临床表现，1998年在日本开展了首次全国性GCA调查。
向日本10717个医疗部门发送了关于1997年接受治疗的GCA患者的第一份调查问卷。共报告了177例患者。在这177例患者中，对第二次调查时有详细临床和流行病学特征的66例GCA患者进行了分析。
1997年日本50岁及以上人群中GCA的患病率为每10万人1.47例。发病平均年龄为71.5岁。男女比例为1:1.7。与其他国家报告的情况相比，永久性完全视力丧失（6.5%）、颌部跛行（15.2%）和风湿性多肌痛（PMR）（30.3%）的关联频率较低。所有患者均接受了皮质类固醇治疗。仅3例（4.5%）患者报告因其他原因死亡。
与其他国家相比，日本GCA的患病率极低。在日本GCA患者中，永久性完全视力丧失、颌部跛行和PMR的临床发现并不常见。
