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[多发性硬化症患者中幽门螺杆菌感染的患病率]

[Prevalence of Helicobacter pylori infection among patients with multiple sclerosis].

作者信息

Wender Mieczysław

出版信息

Neurol Neurochir Pol. 2003 Jan-Feb;37(1):45-8.

PMID:12910828
Abstract

A group of 90 subjects with multiple sclerosis was examined with the serological Helicotest for the presence of antibodies against Helicobacter pylori. Positive results were found in 17 patients (18.9%), which is markedly lower than this infection incidence rate in the population of Poland. The results indicate a lack of connection between the Helicobacter pylori infection and multiple sclerosis. However, it seems reasonable to perform the test in MS patients so as to avoid the risk of the upper alimentary tract complications in the course of intense steroid treatment applied as a standard management of multiple sclerosis relapse.

摘要

对一组90名多发性硬化症患者进行了血清学幽门螺杆菌检测,以检测是否存在抗幽门螺杆菌抗体。17名患者(18.9%)检测结果呈阳性,这明显低于波兰人群中的该感染发病率。结果表明幽门螺杆菌感染与多发性硬化症之间不存在关联。然而,对多发性硬化症患者进行该项检测似乎是合理的,以便在作为多发性硬化症复发标准治疗方法的强化类固醇治疗过程中避免上消化道并发症的风险。

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引用本文的文献

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Mediated Protection against Extra-Gastric Immune and Inflammatory Disorders: The Evidence and Controversies.介导的针对胃外免疫和炎症性疾病的保护作用:证据与争议
Diseases. 2015 Mar 27;3(2):34-55. doi: 10.3390/diseases3020034.
2
Relationship between infection and multiple sclerosis.感染与多发性硬化症之间的关系。
Ann Gastroenterol. 2015 Jul-Sep;28(3):353-356.
3
Helicobacter pylori infection reduces disease severity in an experimental model of multiple sclerosis.幽门螺杆菌感染可降低实验性多发性硬化症模型中的疾病严重程度。
Front Microbiol. 2015 Feb 13;6:52. doi: 10.3389/fmicb.2015.00052. eCollection 2015.
4
Helicobacter pylori and autoimmune disease: cause or bystander.幽门螺杆菌与自身免疫性疾病:病因还是旁观者?
World J Gastroenterol. 2014 Jan 21;20(3):613-29. doi: 10.3748/wjg.v20.i3.613.
5
Relation of helicobacter pylori infection and multiple sclerosis in Iranian patients.伊朗患者中幽门螺杆菌感染与多发性硬化症的关系。
Neurol Int. 2013 Jun 25;5(2):31-3. doi: 10.4081/ni.2013.e10.