Tomisawa Y, Endo M, Kihara S, Saito S, Ishitoya H, Yamasaki K, Aomi S, Nishida H, Kurasawa H
Department of Cardiovascular Surgery, Heart Institute of Japan, Tokyo Women's Medical University, Tokyo, Japan.
Kyobu Geka. 2003 Jul;56(8 Suppl):688-93.
Using standard on-pump procedures, repeat coronary artery bypass grafting (re-CABGs) are associated with a higher morbidity and mortality than first-time CABGs. This retrospective study assessed the clinical outcomes of off-pump re-CABG versus on-pump re-CABG.
From 1983, 2nd CABG and 3rd CABGs were performed in 162 patients at our institute. The early and late results of 142 patients who received standard on-pump re-CABGs and 20 patients who received off-pump re-CABGs were evaluated. The 2 groups were similar in age, sex, preoperative ejection fraction (EF) and number of coronary lesions. However, mean number of distal anastomoses per patient was significantly higher in on-pump (2.0 +/- 0.8) than in off-pump re-CABG (1.4 +/- 0.6) [p = 0.0009].
Hospital mortality tended to be higher in the on-pump group (5.6%) than in the off-pump group (0%) [p = 0.6]. Morbidity in term of total postoperative complications tended to be higher for on-pump (14.1%) than in off-pump (0%) [p = 0.14]. The 5-year survival rate tended to be higher in the off-pump group (100%) than in the on-pump group (80.8 +/- 3.5%) [p = 0.096].
In selected patients, off-pump re-CABG can be a reliable and safe option. The mid-term survival and event-free survival rates achievable with the off-pump option are encouraging.
采用标准的体外循环手术流程,再次冠状动脉旁路移植术(re-CABG)与初次冠状动脉旁路移植术相比,具有更高的发病率和死亡率。本回顾性研究评估了非体外循环再次冠状动脉旁路移植术与体外循环再次冠状动脉旁路移植术的临床结果。
自1983年起,我院对162例患者进行了第二次和第三次冠状动脉旁路移植术。对142例行标准体外循环再次冠状动脉旁路移植术的患者和20例行非体外循环再次冠状动脉旁路移植术的患者的早期和晚期结果进行了评估。两组在年龄、性别、术前射血分数(EF)和冠状动脉病变数量方面相似。然而,体外循环组(2.0±0.8)每位患者的平均远端吻合口数量显著高于非体外循环再次冠状动脉旁路移植术组(1.4±0.6)[p = 0.0009]。
体外循环组的医院死亡率(5.6%)高于非体外循环组(0%)[p = 0.6]。体外循环组术后总并发症的发病率(14.1%)高于非体外循环组(0%)[p = 0.14]。非体外循环组的5年生存率(100%)高于体外循环组(80.8±3.5%)[p = 0.096]。
对于选定的患者,非体外循环再次冠状动脉旁路移植术可以是一种可靠且安全的选择。非体外循环方案可实现的中期生存率和无事件生存率令人鼓舞。