Hagiwara Noriko, Hata Jun, Takaba Hitonori, Saku Yoshisuke
Department of Strokology, St. Mary's Hospital, 422 Tsubuku-honmachi, Kurume, Fukuoka 830-8543, Japan.
No To Shinkei. 2003 Jul;55(7):633-6.
A 76-year-old diabetic woman received epidural catheterization for sigmoid colectomy. Four months later she started to complain of fever and severe lumbago, and finally fell into coma and tetraplegia. She had severe neck stiffness, and lumbar puncture yielded yellowish pus. Methicilin-resistant Staphylococcus aureus (MRSA) was detected in a culture of the epidural pus and blood as a causative organism. Magnetic resonance imaging showed extensive abscess in the posterior epidural space at the level between Th1 and L5. We diagnosed her disease as iatrogenic spinal epidural abscess due to epidural catheterization. After emergent laminectomy and evacuation of abscess, inflammation was gradually improved. She returned to normal except for slight gait disturbance. Spinal epidural abscess often develops rapidly after Staphyloccocus aureus infection. In our case, however, neurological deficits appeared 144 days after insertion of epidural catheter. We must remember that spinal epidural abscess is an important cause of lumbago with high fever, even several months after surgical or catheterial intervention to the spine, for immunocompromised patients with diabetes or neoplasm.
一名76岁的糖尿病女性因乙状结肠切除术接受了硬膜外导管插入术。四个月后,她开始抱怨发热和严重腰痛,最终陷入昏迷并出现四肢瘫痪。她颈部严重僵硬,腰椎穿刺抽出淡黄色脓液。在硬膜外脓液和血液培养物中检测到耐甲氧西林金黄色葡萄球菌(MRSA)作为病原体。磁共振成像显示在胸1至腰5水平的硬膜外后间隙有广泛脓肿。我们将她的疾病诊断为硬膜外导管插入术导致的医源性脊柱硬膜外脓肿。紧急椎板切除和脓肿引流后,炎症逐渐改善。除了轻微的步态障碍外,她恢复了正常。金黄色葡萄球菌感染后,脊柱硬膜外脓肿通常发展迅速。然而,在我们的病例中,神经功能缺损在硬膜外导管插入144天后出现。我们必须记住,对于患有糖尿病或肿瘤的免疫功能低下患者,即使在脊柱进行手术或导管介入数月后,脊柱硬膜外脓肿也是高热伴腰痛的重要原因。