Zhou F Z
Women's Hospital, Zhejiang Medical University, Hangzhou.
Zhonghua Fu Chan Ke Za Zhi. 1992 Jul;27(4):204-5, 249.
The factors related to the prognosis of dysfunctional uterine bleeding (DUB) at puberty were analysed according to the 2 to 15 years' follow-up examination in 44 cases of pubescent DUB. It was found that the establishment of a regular menstrual cycle depends on the duration of disease. Among 19 cases who established a regular cycle, 12 cases (63.2%), 6 cases (31.2%), 1 case (5.3%) with the duration of disease < or = 4 years, 5 to 10 years, and > or = 11 years respectively. The incidence of gynecologic morbidity of pubescent DUB as referred to transfusion, dilatation and curettage, hysterectomy and polycystic ovarian disease was 19/44, 12/44, 1/44 and 5/44 respectively. Of 30 married patients 28 desired children and four of them conceived spontaneously. 9 cases (37.5%) conceived after ovulation induction. It is suggested that the pubescent DUB should be defined as the onset of DUB occurs within 2 years after menarche. Close following up and timely treatment contribute much to the control of the disease and decrease of gynecologic/morbidity.