Vance Mary Lee
Department of Medicine, University of Virginia Health System, P.O. Box 800601, Charlottesville, VA 22908-0746, USA.
Growth Horm IGF Res. 2003 Aug;13 Suppl A:S90-2. doi: 10.1016/s1096-6374(03)00061-3.
Age-related decline in serum testosterone level may present as a constellation of signs and symptoms of hypogonadism known as andropause. However, low testosterone can also be indicative of an underlying pituitary disorder; therefore, careful workup should be performed to distinguish between benign and pathologic conditions in individual men. This article presents an overview of the etiology and pathophysiology of hypogonadism, and offers guidelines for the evaluation of men who should have further testing. The pros and cons of various testosterone formulations are discussed.
血清睾酮水平随年龄下降可能表现为性腺功能减退的一系列体征和症状，即所谓的男性更年期。然而，低睾酮水平也可能提示潜在的垂体疾病；因此，应进行仔细的检查，以区分个体男性的良性和病理性情况。本文概述了性腺功能减退的病因和病理生理学，并为应进行进一步检测的男性提供评估指南。文中还讨论了各种睾酮制剂的优缺点。
