Lysaker Paul H, Lancaster Rebecca S, Nees Michael A, Davis Louanne W
Day Hospital 116H, Roudebush Veterans Administration Medical Center, 1481 West 10th Street, Indianapolis, IN 46202, USA.
Psychiatry Res. 2003 Aug 1;119(3):287-92. doi: 10.1016/s0165-1781(03)00169-0.
This study examined whether levels of emotional distress and impairments in visual memory were uniquely associated with severity of delusions in schizophrenia. Severity of delusions was assessed using select items from the positive component of the Positive and Negative Syndrome Scale among 44 persons with schizophrenia or schizoaffective disorder in a post-acute phase of illness. Emotional distress was assessed using the neuroticism subscale of the NEO Five Factor Inventory, and visual memory was assessed using the Rey Complex Figure Test. Controlling for executive function, visual attention, and verbal memory, a multiple regression analysis revealed that visual memory and neuroticism were each significantly related to severity of delusions, with the two combined accounting for one quarter of the variance. These same variables were unrelated to negative and excitement symptoms. Severity of delusions is linked to both higher levels of neuroticism and greater impairment in visual memory.
本研究考察了情绪困扰水平和视觉记忆损伤是否与精神分裂症妄想严重程度存在独特关联。在44例处于疾病急性期后的精神分裂症或分裂情感性障碍患者中，使用阳性和阴性症状量表阳性分量表中的特定项目评估妄想严重程度。使用大五人格量表中的神经质分量表评估情绪困扰，使用雷氏复杂图形测验评估视觉记忆。在控制执行功能、视觉注意力和言语记忆后，多元回归分析显示，视觉记忆和神经质各自与妄想严重程度显著相关，二者共同解释了四分之一的方差变异。这些变量与阴性症状和激越症状无关。妄想严重程度与较高的神经质水平和更严重的视觉记忆损伤均有关联。
