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Differentiation of genotypic resistance profiles for amprenavir and lopinavir, a valuable aid for choice of therapy in protease inhibitor-experienced HIV-1-infected subjects.

作者信息

Paulsen Denise, Elston Robert, Snowden Wendy, Tisdale Margaret, Ross Lisa

机构信息

Department of International Clinical Virology, GlaxoSmithKline Inc., 5 Moore Drive, Research Triangle Park, NC 27709, USA.

出版信息

J Antimicrob Chemother. 2003 Sep;52(3):319-23. doi: 10.1093/jac/dkg392. Epub 2003 Aug 13.

DOI:10.1093/jac/dkg392
PMID:12917233
Abstract
摘要

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Differentiation of genotypic resistance profiles for amprenavir and lopinavir, a valuable aid for choice of therapy in protease inhibitor-experienced HIV-1-infected subjects.安普那韦和洛匹那韦基因型耐药谱的区分,对有蛋白酶抑制剂治疗史的HIV-1感染患者的治疗选择有重要帮助。
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Ability of different lopinavir genotypic inhibitory quotients to predict 48-week virological response in highly treatment-experienced HIV-infected patients receiving lopinavir/ritonavir.不同洛匹那韦基因型抑制商数预测接受洛匹那韦/利托那韦治疗的高治经验HIV感染患者48周病毒学应答的能力。
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Drug resistance genotypes predict response to amprenavir-containing regimens in highly drug-experienced HIV-1-infected patients.耐药基因型可预测在有大量药物治疗经验的HIV-1感染患者中对含安普那韦治疗方案的反应。
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Selection and recombinant phenotyping of a novel CMX001 and cidofovir resistance mutation in human cytomegalovirus.人巨细胞病毒中新型 CMX001 和更昔洛韦耐药突变的选择和重组表型分析。
Antimicrob Agents Chemother. 2013 Jul;57(7):3321-5. doi: 10.1128/AAC.00062-13. Epub 2013 May 6.