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新生山羊和成年山羊红细胞的体外代谢

In vitro metabolism of red blood cells from newborn and adult goats.

作者信息

Agar N S, Harley J D

出版信息

Biol Neonate. 1976;28(1-2):113-7. doi: 10.1159/000240810.

Abstract

The erythrocytes of newborn and adult goats were studied with respect to GSH stability, GSH regeneration, levels of ATP and 2, 3-DPG, glucose consumption and activities of nine different enzymes of Embden-Meyerhof and pentose phosphate pathways of glucose metabolism. Red cells from newborn goats had significantly higher levels of ATP and 2, 3-DPG. The activities of all the enzymes measured were also significantly greater in the newborn. It is suggested that newborn goats possess red blood cells that are metabolically more active than those of adult goats.

摘要

对新生山羊和成年山羊的红细胞进行了研究,涉及谷胱甘肽(GSH)稳定性、GSH再生、三磷酸腺苷(ATP)和2,3-二磷酸甘油酸(2,3-DPG)水平、葡萄糖消耗以及葡萄糖代谢的糖酵解途径和磷酸戊糖途径中九种不同酶的活性。新生山羊的红细胞中ATP和2,3-DPG水平显著更高。所测定的所有酶的活性在新生山羊中也显著更高。这表明新生山羊的红细胞在代谢上比成年山羊的红细胞更活跃。

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