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1955年至1987年意大利中风死亡率趋势的更新情况。

Update of trends in mortality from stroke in Italy from 1955 to 1987.

作者信息

D'Avanzo B, La Vecchia C, Negri E, Beghi E

机构信息

Istituto di Ricerche Farmacologiche Mario Negri, Milano, Italy.

出版信息

Neuroepidemiology. 1992;11(4-6):196-203. doi: 10.1159/000110932.

DOI:10.1159/000110932
PMID:1291883
Abstract

Mortality form stroke in Italy over the period 1955-1987 was analysed in terms of age-specific, age-standardised death certification rates, and by means of a log-linear model to separate the effects of age, cohort of birth and calendar period of death. In males the overall age-adjusted rate on the world standard population fell from 118.4/100,000 population in 1955-1959 to 72.0 in 1985-1987 and in females from 94.8 in 1955-1959 to 54.7 in 1985-1987. The overall decline in age-standardised rates over the 3 decades was thus 39% for males (averaging 1.7%/year) and 42% for females (averaging 1.9%/year). The declines were even greater in truncated rates from 35 to 64 years: from 80.4 to 41.2/100,000 for males (49%), and from 63.0 to 24.1/100,000 for females (62%). Inspection of age-specific rates shows comparable falls--in relative terms--in early and later middle age. For instance, male rates declined from 70.4 to 38.1/100,000 (46%) at age 50-54, and from 1,151.1 to 584.2/100,000 (50%) at age 70-74. Only above age 75 were the falls smaller. In females aged 50-54 years the decline was 63%, and for those aged 70-74 years it was 59%. In young adults, no appreciable changes were observed in either sex. Thus, the age, period and cohort model showed downwards trends in both the period and cohort effect, except for the most recent cohorts on account of an age-cohort interaction. These favourable trends are discussed in relation to better control of hypertension and the potential impact of other risk factors.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

对1955 - 1987年期间意大利的卒中死亡率,依据年龄特异性、年龄标准化死亡认证率进行了分析,并通过对数线性模型来区分年龄、出生队列和死亡日历时期的影响。在男性中,以世界标准人口计算的总体年龄调整率从1955 - 1959年的118.4/10万人口降至1985 - 1987年的72.0;女性则从1955 - 1959年的94.8降至1985 - 1987年的54.7。因此,在这30年中,年龄标准化率的总体下降幅度男性为39%(平均每年1.7%),女性为42%(平均每年1.9%)。35至64岁年龄段的截短率下降幅度更大:男性从80.4/10万降至41.2/10万(49%),女性从63.0/10万降至24.1/10万(62%)。对年龄特异性率的检查显示,在相对意义上,中年早期和晚期的下降幅度相当。例如,男性50 - 54岁年龄段的发病率从70.4/10万降至38.1/10万(46%),70 - 74岁年龄段从1151.1/10万降至584.2/10万(50%)。只有75岁以上年龄段的下降幅度较小。在50 - 54岁的女性中,下降幅度为63%,70 - 74岁的女性为59%。在年轻人中,两性均未观察到明显变化。因此,年龄、时期和队列模型显示,除了由于年龄 - 队列相互作用导致的最近队列外,时期和队列效应均呈下降趋势。这些有利趋势将结合高血压的更好控制以及其他风险因素的潜在影响进行讨论。(摘要截短至250字)

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