Attar M N, Moulik P K, Salem G D, Rose E L, Khaleeli A A
Department of Medicine, Halton General Hospital, Runcorn, Cheshire, UK.
Int J Clin Pract. 2003 Jul-Aug;57(6):547-8.
Phaeochromocytomas are rare endocrine tumours that secrete excessive amounts of catecholamines and can lead to myocarditis and cardiomyopathy. We report a 63-year-old man with long-standing hypertension and diabetes who presented with dilated cardiomyopathy, which was initially thought to be secondary to ischaemic heart disease. Subsequent coronary angiography was normal. Carvedilol therapy unmasked the characteristic features of phaeochromocytoma. Surgical resection of a right adrenal tumour cured his symptoms, hypertension and diabetes, as well as causing a substantial improvement in cardiac function. Phaeochromocytoma should be considered as a rare cause of dilated cardiomyopathy of uncertain aetiology.
嗜铬细胞瘤是一种罕见的内分泌肿瘤,可分泌过量的儿茶酚胺,并可导致心肌炎和心肌病。我们报告了一名63岁患有长期高血压和糖尿病的男性,他表现为扩张型心肌病,最初被认为是继发于缺血性心脏病。随后的冠状动脉造影正常。卡维地洛治疗揭示了嗜铬细胞瘤的特征性表现。手术切除右侧肾上腺肿瘤治愈了他的症状、高血压和糖尿病,并使心脏功能得到显著改善。嗜铬细胞瘤应被视为病因不明的扩张型心肌病的一种罕见原因。