Lassouw G M, Twijnstra A, Schouten L J, van de Pol M
Department of Neurology, University Hospital Maastricht, The Netherlands.
Neuroepidemiology. 1992;11(4-6):261-6. doi: 10.1159/000110939.
In this report we describe the establishment of a Neuro-Oncology Register (NOR) at the University Hospital of Maastricht, The Netherlands. The register includes data on numbers and types of primary central nervous system (CNS) tumours and neurological complications of systemic cancer. One of the objectives of the register is to determine the incidence rate of neuro-oncological complications in systemic tumours and the incidence and prevalence rates of primary CNS tumours in a well-defined population. The catchment area of the NOR was defined with the help of the Dutch Regional Cancer Register. It involves 140,819 inhabitants and will be considered as our catchment population. At present, 1,168 cases have been recorded since the NOR became operational. All neuro-oncological reports in 1988 were chosen for further analysis (n = 276). We diagnosed 79 metastatic complications from systemic cancer. Metastasis of the brain is the most frequent metastatic complication in our population, followed by epidural metastasis. As in other series, the lung and breast are the most frequently encountered tumour sites. The NOR is a clinically based register which, in co-operation with the Dutch Regional Cancer Register, will generate important epidemiological data on CNS complications.
在本报告中，我们描述了荷兰马斯特里赫特大学医学中心神经肿瘤登记处（NOR）的建立情况。该登记处包括原发性中枢神经系统（CNS）肿瘤的数量和类型以及系统性癌症的神经并发症的数据。该登记处的目标之一是确定系统性肿瘤中神经肿瘤并发症的发病率以及在明确界定人群中原发性CNS肿瘤的发病率和患病率。NOR的服务区域是在荷兰地区癌症登记处的帮助下确定的。它涉及140,819名居民，并将被视为我们的目标人群。自NOR开始运作以来，目前已记录了1,168例病例。我们选取了1988年所有的神经肿瘤报告进行进一步分析（n = 276）。我们诊断出79例系统性癌症的转移并发症。脑转移是我们人群中最常见的转移并发症，其次是硬膜外转移。与其他系列研究一样，肺和乳腺是最常出现肿瘤的部位。NOR是一个基于临床的登记处，它将与荷兰地区癌症登记处合作，生成有关CNS并发症的重要流行病学数据。
