[Trial prevention of the embryolethal properties of suramin in the mouse by adjuvant progesterone].

Suramine, a trypanocidal drug, has an embryo-lethal and teratogenic action in Rodents. Like Triton W.R. 1339 suramine modifies the lysosomes of the visceral yolk sac. In the mouse the attempts to correct the embryolethal action by a simultaneous progesterone treatment failed while the hormonal treatment is capable to suppress the embryolethality in Triton W.R. 1339 treated mice.