Peres G E, Boucher D, Thieblot L
C R Seances Soc Biol Fil. 1975;169(3):587-91.
Effect of cyclofenil on genital function implied organs, is studied in cyclic female rats injected s. cut: 0.5, 5 or 50 mg/kg/day, during 12 days. The treatment increases pituitary, adrenal and uterine weights, decreases ovarian weight, adrenal and ovarien cholesterol. These data suggest that cyclofenil acts directly or undirectly at different levels of hypothalamo-pituitary-genital axis with central inhibition and light peripheral stimulation.
在经皮下注射给予0.5、5或50mg/kg/天环苯咯啶,持续12天的性周期雌性大鼠中,研究了环苯咯啶对生殖功能相关器官的影响。该治疗增加了垂体、肾上腺和子宫的重量,降低了卵巢重量、肾上腺和卵巢胆固醇含量。这些数据表明,环苯咯啶直接或间接作用于下丘脑-垂体-生殖轴的不同水平,具有中枢抑制和轻度外周刺激作用。