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[腹腔镜下宫颈癌根治术联合盆腔及腹主动脉旁淋巴结清扫术的临床评估]

[Clinical evaluation of laparoscopic radical hysterectomy with pelvic and para-aortic lymphadenectomy in patients with cervical cancer].

作者信息

Liang Zhi-qing, Xu Hui-cheng, Xiong Guang-wu, Li Yu-yan, Chen Yong, Wang Lin, Chang Qing, Shi Chang-xu

机构信息

Department of Obstetrics and Gynecology, First Affiliated Hospital, Third Military Medical University, Chongqing 400038, China.

出版信息

Zhonghua Fu Chan Ke Za Zhi. 2003 Jul;38(7):409-11.

Abstract

OBJECTIVE

To evaluate the effective, results and complications in patients with cervical cancer who consented to undergo laparoscopic radical hysterectomy and retroperitoneal lymphadenectomy.

METHODS

In 57 consecutive patients with stage Ia to IIb cervical cancer, laparoscopic radical hysterectomy and lymphadenectomy were performed. Forty-eight patients had squamous cell carcinomas, 7 patients had adenocarcinomas, and 2 patients had adenosquamous carcinomas of the cervix.

RESULTS

All but 2 surgical procedures were completed laparoscopically. The average operative time was 186 min (150 - 320 min). The average blood loss was 168 ml (120 - 700 ml). Average numbers of pelvic and paraaortic lymph nodes removed were 18.6 (12 - 23) and 8.2 (6 - 12), respectively. Eight patients (14.0%) had positive lymph nodes. All surgical margins were macroscopically negative. Operative cystotomies occurred in 2 patients and one patient with venous injuries were repaired laparoscopically. Two other patients underwent laparotomy to control bleeding or repair ascending colon. After surgery, patients passed gas in 2.3 days and self-voided in 10.2 days on average. Follow-up has been provided every 3 months. There have been 3 cases of recurrences, one patient uncontrolled, and one patient ureteral constriction. Three patients have retention of urine.

CONCLUSIONS

Laparoscopic radical hysterectomy and lymphadenectomy can be successfully completed in patients with cervical cancer with acceptable operation complications, a less injury and recovery time, and may become preferred for treating early cervical cancer.

摘要

目的

评估同意接受腹腔镜根治性子宫切除术及腹膜后淋巴结清扫术的宫颈癌患者的疗效、结果及并发症。

方法

对57例连续的Ia期至IIb期宫颈癌患者实施腹腔镜根治性子宫切除术及淋巴结清扫术。48例为鳞状细胞癌,7例为腺癌,2例为宫颈腺鳞癌。

结果

除2例手术外,其余均在腹腔镜下完成。平均手术时间为186分钟(150 - 320分钟)。平均失血量为168毫升(120 - 700毫升)。盆腔及腹主动脉旁淋巴结平均切除数分别为18.6枚(12 - 23枚)和8.2枚(6 - 12枚)。8例(14.0%)患者淋巴结阳性。所有手术切缘肉眼观均为阴性。2例患者发生术中膀胱切开,1例静脉损伤患者在腹腔镜下修复。另外2例患者接受剖腹手术以控制出血或修复升结肠。术后患者平均2.3天排气,10.2天自主排尿。每3个月进行一次随访。有3例复发,1例患者病情未得到控制,1例患者输尿管狭窄。3例患者有尿潴留。

结论

腹腔镜根治性子宫切除术及淋巴结清扫术可成功应用于宫颈癌患者,手术并发症可接受,损伤小、恢复快,可能成为早期宫颈癌治疗的首选方法。

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