Sperber G H
Faculty of Dentistry, University of Alberta, Edmonton, Canada.
Ann Acad Med Singap. 1992 Sep;21(5):708-14.
Craniofacial embryogenesis with emphasis on the mechanisms of morphogenesis as a basis for understanding developmental anomalies is reviewed. A classification of maldevelopment into malformation, deformation and disruption is illustrated by examples. A brief review of the clinical consequences of craniofacial anomalies and possible therapeutic modalities is undertaken.
本文综述了颅面胚胎发生,重点阐述了形态发生机制,以此作为理解发育异常的基础。通过实例说明了发育不良的分类,包括畸形、变形和破坏。还简要回顾了颅面异常的临床后果及可能的治疗方式。