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年轻成年人的动脉瘤性蛛网膜下腔出血:30至40岁患者之间的比较。

Aneurysmal subarachnoid hemorrhage in young adults: a comparison between patients in the third and fourth decades of life.

作者信息

Horiuchi Tetsuyoshi, Tanaka Yuichiro, Hongo Kazuhiro, Kobayashi Shigeaki

机构信息

Department of Neurosurgery, Shinshu University School of Medicine, Matsumoto, Japan.

出版信息

J Neurosurg. 2003 Aug;99(2):276-9. doi: 10.3171/jns.2003.99.2.0276.

Abstract

OBJECT

Aneurysmal subarachnoid hemorrhage rarely occurs in young adults. The aim of this work was to clarify the clinical characteristics of ruptured aneurysms in young adults in the third and fourth decades of life and to compare these two age groups.

METHODS

The authors retrospectively investigated 2493 patients who underwent surgical repair for ruptured cerebral aneurysms during a 14-year period (1988-2001). There were 25 patients (1%) in the third decade of life and 106 patients (4.3%) in the fourth decade. In general, favorable outcome was achieved in both groups. There were significant differences in the sizes and locations of aneurysms between the two age groups. Among patients in the fourth decade of life, the aneurysm was large and was located more often on the anterior cerebral artery.

CONCLUSIONS

In this study the authors summarize the clinical characteristics of a large series of 131 young adult patients with ruptured cerebral aneurysms. Congenital factors as well as hemodynamic stress may contribute to differences in aneurysm size and location between the two age groups.

摘要

目的

动脉瘤性蛛网膜下腔出血在年轻成年人中很少见。本研究的目的是阐明二三十岁的年轻成年人中破裂动脉瘤的临床特征,并比较这两个年龄组。

方法

作者回顾性研究了在14年期间(1988 - 2001年)接受破裂脑动脉瘤手术修复的2493例患者。二三十岁的患者有25例(1%),三四十岁的患者有106例(4.3%)。总体而言,两组患者均取得了良好的预后。两个年龄组之间动脉瘤的大小和位置存在显著差异。在三四十岁的患者中,动脉瘤较大,且更常位于大脑前动脉。

结论

在本研究中,作者总结了131例年轻成年破裂脑动脉瘤患者的临床特征。先天性因素以及血流动力学压力可能导致两个年龄组之间动脉瘤大小和位置的差异。

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