Horiuchi Tetsuyoshi, Tanaka Yuichiro, Hongo Kazuhiro
Department of Neurosurgery, Shinshu University School of Medicine, Matsumoto, Japan.
Neurosurgery. 2005 Mar;56(3):469-75; discussion 469-75. doi: 10.1227/01.neu.0000153926.67713.b8.
Industrialized countries are facing a rapid increase of their senior populations. Consequently, the number of elderly patients with aneurysmal subarachnoid hemorrhage is increasing. The purpose of this study was to assess the results of surgical repair for ruptured aneurysm in elderly patients.
We retrospectively investigated elderly patients (ages 70-89 yr) who were undergoing surgical treatment for ruptured aneurysm during the 15-year period 1988 to 2002 and compared patients in the 8th and 9th decades of life. Generally, patients were treated surgically within 72 hours after ictus.
Of the total of 2835 patients, there were 509 patients (18.0% of total patients) in the 8th decade and 99 patients (3.5%) in the 9th decade of life. Because data were incomplete and patients who received ventricular drainage or ventriculoperitoneal shunt without aneurysmal repair were excluded, 449 and 89 patients in the 8th and 9th decades of life, respectively, were analyzed. No differences in sex, preoperative grade, preoperative computed tomographic findings, location of aneurysm, and aneurysm size were observed between the two decades. Preoperative grade and computed tomographic findings were predictors of favorable outcomes in the 8th and 9th decades. Patient age was a significant predictor of outcome in the 8th but not in the 9th decade.
To the best of our knowledge, this study is the largest series of its kind to date. Advanced age alone does not exclude adequate surgical repair in patients with aneurysmal rupture in the 9th decade of life.
工业化国家正面临老年人口的快速增长。因此,老年动脉瘤性蛛网膜下腔出血患者的数量正在增加。本研究的目的是评估老年患者破裂动脉瘤手术修复的结果。
我们回顾性调查了1988年至2002年15年间接受破裂动脉瘤手术治疗的老年患者(70 - 89岁),并比较了80岁和90岁年龄段的患者。一般来说,患者在发病后72小时内接受手术治疗。
在总共2835例患者中,80岁年龄段有509例患者(占总患者的18.0%),90岁年龄段有99例患者(占3.5%)。由于数据不完整且排除了未进行动脉瘤修复而接受脑室引流或脑室腹腔分流的患者,分别对80岁和90岁年龄段的449例和89例患者进行了分析。两个年龄段在性别、术前分级、术前计算机断层扫描结果、动脉瘤位置和动脉瘤大小方面均未观察到差异。术前分级和计算机断层扫描结果是80岁和90岁年龄段良好预后的预测因素。患者年龄是80岁年龄段预后的重要预测因素,但不是90岁年龄段的。
据我们所知,本研究是迄今为止同类研究中规模最大的系列研究。仅高龄并不排除90岁年龄段动脉瘤破裂患者进行充分的手术修复。