Psarros Thomas, Zouros Alexander, Coimbra Caetano
Department of Neurosurgery, The University of Texas, Southwestern School of Medicine, Dallas, Texas 75390-8855, USA.
J Neurosurg. 2003 Aug;99(2):397-401. doi: 10.3171/jns.2003.99.2.0397.
A 26-year-old woman with obstructive hydrocephalus caused by a cysticercal cyst blocking the left foramen of Monro was initially treated with an external ventriculostomy and subsequent endoscopically assisted cyst resection and septostomy. Postoperatively, the patient developed the clinical syndrome of akinetic mutism, but her condition improved after the administration of the dopaminergic agonist bromocriptine. This result indicates that a disruption in the ascending dopaminergic pathway involved in behavior formation was likely the cause of these neurological symptoms.
一名26岁女性因囊尾蚴囊肿阻塞左侧室间孔导致梗阻性脑积水，最初接受了外部脑室造瘘术，随后进行了内镜辅助囊肿切除术和造瘘术。术后，患者出现了运动不能性缄默症的临床综合征，但在给予多巴胺能激动剂溴隐亭后病情有所改善。这一结果表明，参与行为形成的上行多巴胺能通路中断可能是这些神经症状的原因。
