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显微手术切除声带小结后的脂肪填充:长期结果

Fat augmentation following microsurgical removal of the vocal nodules: long-term results.

作者信息

Hsiung Ming-Wang, Lin Yaoh-Shiang, Su Wan-Fu, Lee Jin-Chin, Wang Hsing-Won

机构信息

Department of Otolaryngology, Tri-Service General Hospital, National Defense Medical Center, No. 325 Cheunggung Road, Sec. 2, Taipei 114, Taiwan, ROC.

出版信息

ORL J Otorhinolaryngol Relat Spec. 2003 May-Jun;65(3):169-75. doi: 10.1159/000072255.

DOI:10.1159/000072255
PMID:12925818
Abstract

While the effectiveness of autogenous fat augmentation after microsurgical removal (FAMSR) of the vocal nodules (VN) has been previously shown in patient treatment programs, relatively little information is available regarding the long-term effectiveness of such a procedure. This paper examines, in retrospect, the long-term effectiveness of FAMSR in patients with VN (n = 41) using pre- and post-FAMSR perceptual acoustic and phonatory function data and videolaryngostroboscopic findings for 33 patients. The mean follow-up time was 18 months. Thirty-three (80.4%) patients displayed excellent results; 4 (9.8%) experienced improvement, and 4 (9.8%) postprocedure failure. Patient phonatory functions showed significant improvements in shimmer, harmonic-to-noise ratio, phonation time (p < 0.05), grade, roughness and breathiness (p < 0.001). The videolaryngostroboscopic rating showed significant improvements in vocal fold edge linearity, vocal fold vibration amplitude, and mucosal wave excursion (p < 0.001). Improvements observed through long-term follow-up tended to be less dramatic in patients with recurrent VN than those with nonrecurrent VN. FAMSR is an easy, safe, and fast procedure which should be considered as an option in treating VN patients who either require surgery or do not have the time or perseverance to complete a lengthy program of speech therapy.

摘要

虽然在患者治疗方案中,此前已显示显微手术切除声带小结(VN)后自体脂肪填充(FAMSR)的有效性,但关于该手术的长期有效性的信息相对较少。本文回顾性研究了FAMSR对VN患者(n = 41)的长期有效性,使用了FAMSR前后的感知声学和发声功能数据以及33例患者的电子喉镜频闪检查结果。平均随访时间为18个月。33例(80.4%)患者效果极佳;4例(9.8%)有改善,4例(9.8%)术后失败。患者的发声功能在振幅微扰、谐波噪声比、发声时间(p < 0.05)、等级、粗糙度和气息声(p < 0.001)方面有显著改善。电子喉镜频闪检查评分显示声带边缘线性、声带振动幅度和黏膜波偏移有显著改善(p < 0.001)。通过长期随访观察到,复发性VN患者的改善往往不如非复发性VN患者显著。FAMSR是一种简便、安全且快速的手术,对于需要手术或没有时间或毅力完成冗长言语治疗方案的VN患者,应将其视为一种治疗选择。

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