Rainville Constant, Giroire Jean-Michel, Periot Maryline, Cuny Emmanuel, Mazaux Jean-Michel
Centre de Recherche, Institut Universitaire de Gériatrie de Montréal, Montréal, Canada.
Neurocase. 2003 Aug;9(4):356-67. doi: 10.1076/neur.9.4.356.15548.
Deep-seated cerebral lesions have been known to cause various cognitive impairments. In order to study the impact of these lesions on cognitive functioning, in particular on executive functions and spatial abilities, an investigation was carried out on a right-handed patient with lesions in the subcortical structures of the right hemisphere. Findings revealed a complex pattern of neuropsychological impairments that included a memory deficit, neglect and anosognosia. In addition, there was a severe executive function syndrome. Finally, observations show impairments in spatial abilities, usually attributed to right parietal damage. There was no obvious language deficit. The pattern of deficits was interpreted as a disconnection syndrome.
深部脑损伤已知会导致各种认知障碍。为了研究这些损伤对认知功能的影响,特别是对执行功能和空间能力的影响,对一名右半球皮质下结构受损的右利手患者进行了调查。研究结果显示出一种复杂的神经心理学损伤模式,包括记忆缺陷、忽视和疾病感缺失。此外,还存在严重的执行功能综合征。最后,观察结果表明空间能力受损,通常归因于右侧顶叶损伤。没有明显的语言缺陷。这种缺陷模式被解释为一种分离综合征。