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[使用天然富含碳13的乙醇进行代谢研究]

[Use of ethanol naturally enriched in carbon 13 for metabolic studies].

作者信息

Bricout J, Le Bourhis B, Koziet J

出版信息

C R Seances Soc Biol Fil. 1975;169(4):904-11.

PMID:129261
Abstract

The ratio of carbon 13 to carbon 12 is higher in organic substances which originate from corn or cane, as compared to most higher plants. Cane alcohol or corn alcohol are enriched in carbon 13 as compared to common European foods. This discovery provided a new technique for alcohol metabolism studies with animals or men. The ratio of carbon 13 to carbon 12 is measured by mass spectrometry in the carbon dioxide expired after administration of cane or corn alcohol. This ratio increases significantly and reaches a maximum when the blood alcohol level has decreased considerably.

摘要

与大多数高等植物相比,源自玉米或甘蔗的有机物质中碳13与碳12的比例更高。与欧洲常见食物相比,甘蔗酒精或玉米酒精富含碳13。这一发现为动物或人体酒精代谢研究提供了一项新技术。通过质谱法测量摄入甘蔗酒精或玉米酒精后呼出的二氧化碳中碳13与碳12的比例。当血液酒精水平大幅下降时,该比例会显著增加并达到最大值。

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