可重复使用的沸石催化剂存在下萘的区域选择性二烷基化研究

Study of regioselective dialkylation of naphthalene in the presence of reusable zeolite catalysts.

作者信息

Smith Keith, Roberts Simon D, el-Hiti Gamal A

机构信息

Centre for Clean Chemistry, Department of Chemistry, University of Wales Swansea, Singleton Park, Swansea, UK SA2 8PP.

出版信息

Org Biomol Chem. 2003 May 7;1(9):1552-9. doi: 10.1039/b212775j.

DOI:10.1039/b212775j

PMID:12926286

Abstract

Highly regioselective dialkylation of naphthalene using various alkylating agents can be achieved over zeolite catalysts. For example, the tert-butylation of naphthalene (1) using tert-butanol in cyclohexane over a dealuminated H-Mordenite (HM) zeolite has been optimised to give a 60% yield of 2.6-di-tert-butylnaphthalene (3) with a 2.6/2.7 ratio of over 50. This has been achieved by varying the reaction time, temperature, solvent, pressure, amount of tert-butanol, solvent and catalyst, Si/Al ratio of the catalyst, and the mode of addition. The zeolites can be easily regenerated by heating and reused.

摘要

在沸石催化剂作用下，使用各种烷基化剂可实现萘的高度区域选择性二烷基化。例如，在脱铝的丝光沸石（HM）沸石上，萘（1）与叔丁醇在环己烷中进行叔丁基化反应，已通过优化反应时间、温度、溶剂、压力、叔丁醇用量、溶剂和催化剂、催化剂的硅铝比以及添加方式，使2,6 - 二叔丁基萘（3）的产率达到60%，2,6/2,7比例超过50。这些沸石可通过加热轻松再生并重复使用。