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[缺氧和高碳酸血症时的膈肌血流]

[Diaphragmatic blood flow in hypoxia and hypercapnia].

作者信息

Sanotskaia N V, Matseievskiĭ D D, Aleĭnikov S O

出版信息

Biull Eksp Biol Med. 1992 Dec;114(12):580-3.

PMID:1292676
Abstract

By means of ultrasonic method, used in acute experiments on cats with closed abdominal cavity under nembutal narcosis, we studied the linear and volumetric blood flow velocity in the left phrenic artery, vascular resistance, systemic blood pressure, lung ventilation, arterial blood gases during different degrees of hypoxia and hypercapnia. It was shown that hypoxia and hypercapnia resulted in a decrease of the phrenic artery vascular resistance and an increase of the blood flow in the phrenic artery, not always proportional to hypoxia and hypercapnia degree. The correlation of an increase of the lung ventilation with an increase of the blood flow in the phrenic artery depends on the factor causing activation of the diaphragm performance. Some extreme conditions (prolonged asphyxia, blood loss, the exposure to 3% O2) lower phrenic vascular resistance, providing maximal blood supply of the diaphragm.

摘要

通过超声方法,在戊巴比妥麻醉下对腹腔封闭的猫进行急性实验,我们研究了不同程度的缺氧和高碳酸血症期间左膈动脉的线性和容积血流速度、血管阻力、全身血压、肺通气、动脉血气。结果表明,缺氧和高碳酸血症导致膈动脉血管阻力降低,膈动脉血流增加,但并不总是与缺氧和高碳酸血症程度成正比。肺通气增加与膈动脉血流增加之间的相关性取决于引起膈肌活动激活的因素。一些极端情况(长时间窒息、失血、暴露于3%氧气)会降低膈血管阻力,为膈肌提供最大血液供应。

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