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[不同气体介质中的肺循环]

[Pulmonary circulation in different gaseous media].

作者信息

Sanotskaia I V, Matsievskiĭ D D

出版信息

Biull Eksp Biol Med. 1985 Sep;100(9):286-9.

PMID:4041591
Abstract

The ultrasonic method was used in acute experiments on cats with an open (under artificial lung ventilation) and closed chest to explore lung circulation in a changed gaseous medium. Moderate hypoxia (10% O2) and hypercapnia (5, 10% CO2) induce a 10-15% decrease in the lung blood flow in the inferolobular pulmonary artery in the presence of unchanged or slightly elevated minute volume of the heart. The higher hypoxia (5% O2) provokes inconclusive changes in the lung blood flow: biphasic response or increase. It is assumed that considerable elevation of blood pressure in the common pulmonary artery in all the cases points to vasoconstriction that occurs under the effect of hypoxia and hypercapnia.

摘要

在对开胸(人工肺通气)和闭胸猫进行的急性实验中,采用超声方法在变化的气体介质中探究肺循环。在心脏每分钟输出量不变或略有升高的情况下,中度缺氧(10%氧气)和高碳酸血症(5%、10%二氧化碳)会导致下叶肺动脉的肺血流量减少10 - 15%。更高程度的缺氧(5%氧气)会引发肺血流量不确定的变化:双相反应或增加。据推测,在所有情况下,肺总动脉血压的显著升高表明在缺氧和高碳酸血症的作用下发生了血管收缩。

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