Chang Caren
Department of Cell Biology and Molecular Genetics, HJ Patterson Hall, University of Maryland, College Park, MD 20742-5815, USA.
Trends Plant Sci. 2003 Aug;8(8):365-8. doi: 10.1016/S1360-1385(03)00156-0.
Ethylene hormone responses are negatively regulated by the CTR1 protein, which has similarity to mitogen-activated protein kinase kinase kinases (MAPKKKs). Because of this similarity, it has long been speculated that ethylene signal transduction involves a MAPK cascade. Now, a recent paper provides compelling evidence for an ethylene-activated MAPK pathway. The implication is that CTR1 and the newly identified MAPKK and MAPKs comprise a MAPK module that regulates ethylene responses in plants.
乙烯激素反应受到CTR1蛋白的负调控，CTR1蛋白与丝裂原活化蛋白激酶激酶激酶（MAPKKKs）具有相似性。由于这种相似性，长期以来人们一直推测乙烯信号转导涉及一个MAPK级联反应。现在，最近的一篇论文为乙烯激活的MAPK途径提供了令人信服的证据。这意味着CTR1以及新发现的MAPKK和MAPKs组成了一个调节植物乙烯反应的MAPK模块。
