[Botulinum toxin in headache].

Use of botulinum toxin in headache is a recent method. More and more studies are dedicated to this method. However, despite the large number of published studies, results are contradictory. It is actually difficult to conclude that this therapy is effective or not due to the disparity of clinical studies. Nevertheless, some results are encouraging and studies with a large number of patients have to be done. Here, we take stock about pathophysiological data on the effect of botulinum toxin on pain. Then, we'll report a review of clinical studies available on literature.