Miura Hiroyuki, Shimamura Hideki, Tsuchiya Kazuhiro, Hatao Ei-ichi, Kusama Hiroshi, Matsuoka Takeshi
Fifth Department of Internal Medicine, Tokyo Medical University, 3-20-1, Chuo, Ami, Inashiki, Ibaraki 300-0395, Japan.
Eur Radiol. 2003 Sep;13(9):2192-5. doi: 10.1007/s00330-002-1657-y. Epub 2002 Oct 9.
Lymphomatoid granulomatosis (LG) is an angiocentric and angiodestructive lymphoproliferative disease that mainly involves the lung. Thirty percent of patients with LG have neurological symptoms. We report serial changes in MRI of a patient with LG of the brain. Postcontrast MRI demonstrated multiple punctate and linear areas that preceded hemorrhage, as indicated by hypointensity with surrounding hyperintensity on subsequent T2-weighted images. The diagnostic value of these lesions observed with contrast MR images is discussed. We consider that enhancing areas correspond to walls of small vessels affected by LG.
淋巴瘤样肉芽肿病（LG）是一种主要累及肺部的血管中心性和血管破坏性淋巴增殖性疾病。30%的LG患者有神经症状。我们报告了1例脑部LG患者的MRI系列变化。增强后MRI显示多个点状和线状区域，随后的T2加权图像上表现为低信号，周围有高信号，提示这些区域先于出血出现。讨论了对比剂增强MR图像上观察到的这些病变的诊断价值。我们认为强化区域对应于受LG影响的小血管壁。
