甲状腺激素对分离的大鼠脂肪细胞5'-核苷酸酶的影响。

Effect of thyroid hormones on 5'-nucleotidase of isolated rat fat cells.

作者信息

Gandarias J M, Goiriena J J, Rueda E, Fernandez B M

机构信息

Departamento de Fisiología, Facultad de Medicina, Universidad del Pais Vasco, Bilbao, España.

出版信息

Enzyme. 1992;46(4-5):229-33. doi: 10.1159/000468792.

DOI:10.1159/000468792

PMID:1292932

Abstract

5'-Nucleotidase was measured in isolated fat cells from normal, hypothyroid and hyperthyroid rats. This was done to find out whether thyroid hormones had an effect on the production of adenosine by the fat cell. The results showed that 5'-nucleotidase is modified when the rats received injections of 3,3',5-triiodo-L-thyronine (T3). There was no change in the enzyme in hypothyroidism or when T3 was added to incubation of cells.

摘要

在正常、甲状腺功能减退和甲状腺功能亢进大鼠的分离脂肪细胞中测定了5'-核苷酸酶。这样做是为了弄清楚甲状腺激素是否对脂肪细胞产生腺苷有影响。结果表明，当大鼠注射3,3',5-三碘-L-甲状腺原氨酸（T3）时，5'-核苷酸酶会发生改变。在甲状腺功能减退时或向细胞培养物中添加T3时，该酶没有变化。