Shimono N, Ishimaru T, Takaki K, Okada K, Nagafuchi S, Takemori K, Tsutsui T, Sawae Y
First Department of Internal Medicine, Faculty of Medicine, Kyushu University, Fukuoka.
Fukuoka Igaku Zasshi. 1992 Dec;83(12):420-5.
We examined the clinical records of patients from whom S. milleri was isolated at Kyushu University Hospital from January 1987 through December 1988. Sixty-one patients were treated in 64 episodes with drainage or antibiotics. Oral and nasopharyngeal infections were observed in 27 cases, intrathoracic infections in 13, urogenital infections in 8, intraabdominal infections in 6 and skin and subcutaneous infections in 6. Except for acute bronchitis and urogenital infections, all of them were suppurative. As to underlying diseases, 21 patients had malignancies and 6 had diabetes mellitus. Leukocytopenia was not observed in any of the patients. S. milleri can be eradicated by treatment but it is sometimes replaced by other organisms. However, considering its tendency to cause suppurative infections, its pathogenic significance should be taken into account and patients should undergo surgical drainage combined with antibiotic therapy.
我们查阅了1987年1月至1988年12月在九州大学医院分离出米勒链球菌的患者的临床记录。61例患者接受了64次引流或抗生素治疗。观察到27例口腔和鼻咽部感染，13例胸腔内感染，8例泌尿生殖系统感染，6例腹腔内感染，6例皮肤和皮下感染。除急性支气管炎和泌尿生殖系统感染外，其余均为化脓性感染。关于基础疾病，21例患者患有恶性肿瘤，6例患有糖尿病。所有患者均未观察到白细胞减少。米勒链球菌可通过治疗根除，但有时会被其他病原体取代。然而，考虑到其引起化脓性感染的倾向，应重视其致病意义，患者应接受手术引流并联合抗生素治疗。
