Garde S V, Sheth A R
Institute for Research in Reproduction (ICMR), Bombay, India.
Indian J Exp Biol. 1992 Nov;30(11):1006-11.
Immunoreactive 10.5 KDa moiety of inhibin and hFSH was present in the baboon endometrium during menstrual cycle, early pregnancy and in castrated animals treated with steroid hormones, estrogen and/or progesterone. Endometrial differences during the menstrual cycle altered the intensity of immunostaining of inhibin and FSH. Maximum staining was observed in late luteal phase for both the hormones. In early pregnancy (35th day), the conceptus increased the staining for inhibin in the adjoining endometrial glands. Treatment of castrated animals with steroids for 14 days caused increased staining for inhibin. Maximum staining was observed when treated with estradiol or progesterone, whereas combination of estrogen and progesterone treatment decreased the staining reaction. In conclusion, both inhibin and FSH were localized in baboon endometrium and were under the influence of estrogen and progesterone.
在月经周期、妊娠早期以及用甾体激素、雌激素和/或孕激素处理的去势动物的狒狒子宫内膜中，存在抑制素和人促卵泡激素（hFSH）的免疫反应性10.5 kDa部分。月经周期中的子宫内膜差异改变了抑制素和促卵泡激素的免疫染色强度。两种激素在黄体晚期均观察到最大染色。在妊娠早期（第35天），孕体增加了相邻子宫内膜腺体中抑制素的染色。用甾体激素处理去势动物14天导致抑制素染色增加。用雌二醇或孕酮处理时观察到最大染色，而雌激素和孕激素联合处理则降低了染色反应。总之，抑制素和促卵泡激素均定位于狒狒子宫内膜中，并受雌激素和孕激素的影响。
