经 TLS/FUS-CHOP 融合转录本证实的黏液样脂肪肉瘤。
Myxoid liposarcoma confirmed by TLS/FUS-CHOP fusion transcripts.
作者信息
Huang Yau-Li, Hong Hong-Shang, Kuo Tseng-Tong, Chung Chi-Jung
机构信息
Department of Dermatology, Chang Gung Memorial Hospital, 199 Tung-Hwa North Road, Taipei 105, Taiwan.
出版信息
Dermatol Surg. 2003 Sep;29(9):980-1. doi: 10.1046/j.1524-4725.2003.29265.x.
Abstract
Described here is the use of detecting TLS/FUS-CHOP fusion transcripts to confirm the diagnosis of a myxoid liposarcoma by nested reverse transcription-polymerase chain reaction assay using archival formalin-fixed, paraffin-embedded tissues of a young man with a benign-looking myxoid tumor on his upper extremity, which is often misdiagnosed clinically or histopathologically as a benign tumor.
摘要
本文描述了通过巢式逆转录聚合酶链反应检测TLS/FUS-CHOP融合转录本，以确诊一名上肢患有外观良性黏液样肿瘤的年轻男性的黏液样脂肪肉瘤。该肿瘤在临床或组织病理学上常被误诊为良性肿瘤，其存档的福尔马林固定石蜡包埋组织用于此项检测。
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