Fink K G, Hutarew G, Pytel A, Esterbauer B, Jungwirth A, Dietze O, Schmeller N T
Department of Urology and Andrology, St. Johannsspital, Salzburg, Austria.
BJU Int. 2003 Sep;92(4):385-8. doi: 10.1046/j.1464-410x.2003.04350.x.
To compare the efficiency of different transrectal ultrasonography (TRUS)-guided prostate biopsy techniques for detecting prostate cancer.
In all, 81 prostates from radical prostatectomy were used and two consecutive sets of sextant biopsies and one 10-core biopsy taken in each specimen. The 10-core biopsy consisted of a sextant biopsy and four cores from the far lateral areas of the prostate. To simulate a transrectal biopsy procedure, all biopsies were taken under TRUS guidance.
In the first set of sextant biopsies 44 prostate cancers (54%) were detected and in the second set 51 (63%). Combining both sets of sextant biopsies 57 (70%) of the carcinomas were detected. One set of 10-core biopsies detected 66 (82%) of all prostate cancers. Overall, with the 10-core biopsies 16% more prostate tumours were diagnosed than with two consecutive sets of sextant biopsies. To find the same number of prostate cancers as with the 10-core technique, 14% of patients undergoing sextant biopsy would require a second set and 11% at least a third set of biopsies.
The 10-core prostate biopsy technique is superior to the commonly used sextant technique and could spare patients unnecessary repeated biopsy. Even after including a second set of sextant biopsies, the total detection rate with these 12 biopsies was inferior to the 10-core technique.
比较不同经直肠超声（TRUS）引导下前列腺穿刺活检技术检测前列腺癌的效率。
共使用81例前列腺癌根治术切除的前列腺标本，每个标本连续进行两组六分区活检和一组10针活检。10针活检包括六分区活检以及来自前列腺外侧区的4针活检。为模拟经直肠活检过程，所有活检均在TRUS引导下进行。
在第一组六分区活检中检测到44例前列腺癌（54%），第二组检测到51例（63%）。两组六分区活检联合后，检测到57例（70%）癌。一组10针活检检测到所有前列腺癌中的66例（82%）。总体而言，10针活检诊断出的前列腺肿瘤比连续两组六分区活检多16%。要发现与10针活检技术相同数量的前列腺癌，六分区活检患者中14%需要进行第二组活检，11%至少需要进行第三组活检。
10针前列腺活检技术优于常用的六分区活检技术，可避免患者进行不必要的重复活检。即使包括第二组六分区活检，这12次活检的总检出率仍低于10针活检技术。
