Sengar D P, Rashid A, Perelmutter L, Harris J E
Clin Exp Immunol. 1975 May;20(2):249-55.
Mixed leucocyte culture blocking factor activity (MLC-BFA) in the plasma of haemodialysis patients appears as a result of recent blood transfusions and is concentrated in IgG fractions of the blocking serum. Four patients neither developed lymphocytotoxins nor MLC-BFA in spite of having received multiple blood transfusions. Such 'unresponsive' recipients had an excellent clinical course upon receiving an allograft.
血液透析患者血浆中的混合白细胞培养阻断因子活性(MLC - BFA)是近期输血的结果,且集中在阻断血清的IgG组分中。尽管有4名患者接受了多次输血,但既未产生淋巴细胞毒素,也未出现MLC - BFA。这些“无反应性”受者在接受同种异体移植后临床过程良好。