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接受血液透析的尿毒症患者血浆中的淋巴细胞毒素和混合白细胞培养阻断因子活性

Lymphocytotoxins and mixed leucocyte culture blocking factor activity in the plasma of uraemic patients undergoing haemodialysis.

作者信息

Sengar D P, Rashid A, Perelmutter L, Harris J E

出版信息

Clin Exp Immunol. 1975 May;20(2):249-55.

Abstract

Mixed leucocyte culture blocking factor activity (MLC-BFA) in the plasma of haemodialysis patients appears as a result of recent blood transfusions and is concentrated in IgG fractions of the blocking serum. Four patients neither developed lymphocytotoxins nor MLC-BFA in spite of having received multiple blood transfusions. Such 'unresponsive' recipients had an excellent clinical course upon receiving an allograft.

摘要

血液透析患者血浆中的混合白细胞培养阻断因子活性(MLC - BFA)是近期输血的结果,且集中在阻断血清的IgG组分中。尽管有4名患者接受了多次输血,但既未产生淋巴细胞毒素,也未出现MLC - BFA。这些“无反应性”受者在接受同种异体移植后临床过程良好。

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A semimicro mixed leukocyte culture test.半微量混合白细胞培养试验。
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Blood transfusions and unresponsiveness to HL-A.输血与对组织相容性白细胞抗原(HL-A)无反应性
Transplantation. 1973 Dec;16(6):649-54. doi: 10.1097/00007890-197312000-00017.

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