Kong Ling-Yi, Zhi Fei
Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, China.
J Asian Nat Prod Res. 2003 Sep;5(3):183-7. doi: 10.1080/1028602031000082034.
A new angular dihydropyrancoumarin named wulongensin A, along with five known coumarins, (-)-anomalin, umbelliferone, (-)-smyrinol, 3'(S),4'(S)-disenecioyloxy-3',4'-dihydroseselin, (+)-trans-khellactone, was isolated from the root of Peucedanum wulongense. The structure of wulongensin A was established as 3'(R)-angeloyloxy-4'(R)-isovaleryloxy-3',4'-dihydroseselin by spectroscopic methods and the absolute configurations were deduced by chemical correlations with known compounds.
从长序前胡根中分离得到一个新的角型二氢吡喃香豆素，命名为乌龙前胡素A，以及5个已知香豆素，即（-）-异补骨脂内酯、伞形花内酯、（-）-异邪蒿内酯、3'（S），4'（S）-二千里光酰氧基-3'，4'-二氢邪蒿内酯、（+）-反式凯刺内酯。通过光谱方法确定了乌龙前胡素A的结构为3'（R）-当归酰氧基-4'（R）-异戊酰氧基-3'，4'-二氢邪蒿内酯，并通过与已知化合物的化学关联推导了其绝对构型。
