Cao Wei, Liu Li, Tong Ming-hua
Department of Clinical Laboratory, Second Xiangya Hospital, Central South University, Changsha 410011, China.
Hunan Yi Ke Da Xue Xue Bao. 2003 Apr;28(2):177-9.
To investigate the infectious distribution and resistant of Neisseria gonorrhoeae, Mycoplasma, and Chlamydia trachomatis in the chronic prostatitis.
The identification and susceptibility of Neisseria gonorrhoeaes and Mycoplasmas were detected by a cultural method. The nitrocefin test was used to detect the beta-lactamase in Neisseria gonorrhoeae strains. Chlamydia trachomatis was identificated by a monoclonal gold labeled antibody method.
A total of 2,900 prostatic fluids were detected and the rates of isolation of Neisseria gonorrhoeae, Mycoplasma, and Chlamydia trachomatis were 3.3%, 12.8%, and 0.9%, respectively. The prevalence of beta-lactamase in Neisseria gonorrhoeae strains was 12.6%. The resistant percentages of Neisseria gonorrhoeae strains were 73.7% to penicillin and 91.6% to ciprofloxacin and ofloxacin respectively, but the susceptibility to spectinomycin, cephalosporin and cefoxitin was good. The resistant rates of Mycoplasma to tetracycline, acetylspiramycin, erythromycin, and ofloxacin were 50.0% or more, but the susceptibilities to roxithromycin, doxycyclin, levofloxacin, minocyclin, josamycin, and azithromycin were about 70.0%-80.0%.
The isolation rate of Mycoplasma is higher than that of Neisseria gonorrhoeae and Chlamydia trachomatis in the chronic prostatitis. It is important to detect the susceptibility of Neisseria gonorrhoeae and Mycoplasma for the use of antibiotics in reason.
探讨慢性前列腺炎中淋病奈瑟菌、支原体及沙眼衣原体的感染分布及耐药情况。
采用培养法检测淋病奈瑟菌和支原体的鉴定及药敏情况。用硝噻吩试验检测淋病奈瑟菌菌株中的β-内酰胺酶。采用单克隆金标抗体法鉴定沙眼衣原体。
共检测2900份前列腺液,淋病奈瑟菌、支原体及沙眼衣原体的分离率分别为3.3%、12.8%和0.9%。淋病奈瑟菌菌株中β-内酰胺酶的流行率为12.6%。淋病奈瑟菌菌株对青霉素的耐药率为73.7%,对环丙沙星和氧氟沙星的耐药率分别为91.6%,但对大观霉素、头孢菌素和头孢西丁的敏感性良好。支原体对四环素、乙酰螺旋霉素、红霉素和氧氟沙星的耐药率达50.0%以上,但对罗红霉素、多西环素、左氧氟沙星、米诺环素、交沙霉素和阿奇霉素的敏感性约为70.0%-80.0%。
慢性前列腺炎中支原体的分离率高于淋病奈瑟菌和沙眼衣原体。合理使用抗生素时检测淋病奈瑟菌和支原体的药敏情况很重要。