[三种恶性肿瘤患者血清唾液酸检测及其临床意义]
[Detection of serum sialic acid in three kinds of malignant tumor and its clinical significance].
作者信息
Liang Xiang-hui, Liang Xian-ming, Yi Bin
机构信息
Clinical Laboratory, Xiangya Hospital, Central South University, Changsha 410008, China.
出版信息
Hunan Yi Ke Da Xue Xue Bao. 2003 Feb 28;28(1):65-6.
OBJECTIVE
To study the diagnostic significance and clinical effect of the detection of serum sialic acid (SA) in three kinds of malignant tumor.
METHODS
The specimens (172) were divided into the healthy control group (100), lung cancer group (31), leukemia group (28) and rectual cancer group (17), and then the serum SA concentration in those specimens was analyzed and statistic analysis was conducted.
RESULTS
The SA levels of the malignant tumor groups before and after the treatment were significantly higher than those of the healthy control group (P < 0.05). The positive rates of serum SA in the lung cancer group, leukemia group and rectual group were 84%, 79% and 71%.
CONCLUSION
The SA concentration was significantly increased in the malignant patients so SA can be used as an indication of cancer, and it can be widely used in the diagnosis and inspection of malignant tumor.
目的
探讨血清唾液酸（SA）检测在三种恶性肿瘤中的诊断意义及临床效果。
方法
将172份标本分为健康对照组（100例）、肺癌组（31例）、白血病组（28例）和直肠癌组（17例），然后对这些标本中的血清SA浓度进行分析并进行统计学分析。
结果
治疗前后恶性肿瘤组的SA水平均显著高于健康对照组（P < 0.05）。肺癌组、白血病组和直肠癌组血清SA的阳性率分别为84%、79%和71%。
结论
恶性肿瘤患者的SA浓度显著升高，因此SA可作为癌症的一项指标，广泛应用于恶性肿瘤的诊断和检查。
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