Zhu Fu-fan, Sun Wen-xia, Huang Jian
Department of Obstetrics and Gynecology, Second Xiangya Hospital, Central South University, Changsha 410011, China.
Hunan Yi Ke Da Xue Xue Bao. 2003 Feb 28;28(1):70-2.
To explore the relationship between anticardiolipin antibodies (ACA) and abortion.
The level of serum ACA in 93 abortion women (abortion group) and 80 normal pregnant women (control group) was determined by the enzyme linked immunoabsorbent assay. The abortion group included threatened abortion (n = 62), inevitable abortion (n = 21), and missed abortion (n = 10).
The positive rate of ACA in the abortion group was significantly higher than that in the control group (P < 0.05). The positive rate of ACA in pregnant women with a history of abortion was significantly higher than that in those women without a history of abortion (P < 0.05). The positive rate of ACA was not significantly different between habitual abortion and spontaneous abortion (P > 0.05).
Anticardiolipin antibodies may induce abortion, but it is not related to habitual abortion.
探讨抗心磷脂抗体（ACA）与流产之间的关系。
采用酶联免疫吸附测定法检测93例流产妇女（流产组）和80例正常孕妇（对照组）血清ACA水平。流产组包括先兆流产（n = 62）、难免流产（n = 21）和稽留流产（n = 10）。
流产组ACA阳性率显著高于对照组（P < 0.05）。有流产史孕妇的ACA阳性率显著高于无流产史孕妇（P < 0.05）。习惯性流产与自然流产的ACA阳性率差异无统计学意义（P > 0.05）。
抗心磷脂抗体可能诱发流产，但与习惯性流产无关。
