• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

通过自氧化-迈克尔加成反应立体选择性合成2,2-双（C-支链）吡喃葡萄糖苷-3-酮糖。

Stereoselective synthesis of 2,2-bis(C-branched-chain)glucopyranosid-3-ulose via an autoxidation-Michael addition reaction.

作者信息

Liu Hong-Min, Zhang Fuyi, Zou Da-Peng

机构信息

Department of Chemistry, Zhengzhou University, Zhengzhou, 450052, PR China.

出版信息

Chem Commun (Camb). 2003 Aug 21(16):2044-5. doi: 10.1039/b306227a.

DOI:10.1039/b306227a
PMID:12934903
Abstract

2,2-Bis(C-branched-chain)glucopyranosid-3-uloses, designed for the preparation of biologically active natural product iridoid derivatives, are synthesized selectively by the new reaction of butenolide-containing sugar with active methylene compounds, and the new reaction is clarified as autoxidation followed by Michael addition of carbanion.

摘要

用于制备生物活性天然产物环烯醚萜衍生物的2,2-双（C-支链）吡喃葡萄糖苷-3-酮，通过含丁烯内酯的糖与活性亚甲基化合物的新反应选择性合成，该新反应被阐明为自动氧化后碳负离子的迈克尔加成反应。

相似文献

1
Stereoselective synthesis of 2,2-bis(C-branched-chain)glucopyranosid-3-ulose via an autoxidation-Michael addition reaction.通过自氧化-迈克尔加成反应立体选择性合成2,2-双（C-支链）吡喃葡萄糖苷-3-酮糖。
Chem Commun (Camb). 2003 Aug 21(16):2044-5. doi: 10.1039/b306227a.
2
Novel autoxidation and Michael addition of a butenolide-containing sugar leading to a C-branched-chain glucopyranosidulose, and X-ray structure of intermediates.含丁烯内酯糖的新型自氧化和迈克尔加成反应生成C-支链吡喃葡萄糖酮糖及其中间体的X射线结构
Carbohydr Res. 2003 Aug 12;338(17):1737-43. doi: 10.1016/s0008-6215(03)00257-x.
3
Synthesis of branched-chain sugar derivatives from 1,2;5,6-di-O-isopropylidene-alpha-D-ribo-hexofuranos-3-ulose and 1,2;4,5-di-O-isopropylidene-beta-D-erythro-2-hexulopyranos-3-ulose.由1,2;5,6-二-O-异亚丙基-α-D-核糖己呋喃糖-3-酮和1,2;4,5-二-O-异亚丙基-β-D-赤藓糖-2-己酮糖-3-酮合成支链糖衍生物。
Carbohydr Res. 2000 Dec 1;329(4):901-6. doi: 10.1016/s0008-6215(00)00229-9.
4
Stereoselective synthesis of C-glycosides from carboxylic acids: the tandem Tebbe-Claisen approach.从羧酸立体选择性合成C-糖苷：串联Tebbe-Claisen方法。
Org Biomol Chem. 2003 Nov 7;1(21):3772-86. doi: 10.1039/b306675b.
5
Synthesis of glycosides of 3-deoxy-4-thiopentopyranosid-2-uloses and their reduction products: 3-deoxy-4-thiopentopyranosides.
Carbohydr Res. 2002 Nov 19;337(21-23):2069-76. doi: 10.1016/s0008-6215(02)00292-6.
6
Toward the synthesis of fine chemicals from lactose: preparation of D-xylo and L-lyxo-aldohexos-5-ulose derivatives.从乳糖合成精细化学品：D-木糖型和L-来苏糖型己醛糖-5-酮衍生物的制备
Carbohydr Res. 2009 Apr 21;344(6):717-24. doi: 10.1016/j.carres.2009.01.014. Epub 2009 Jan 19.
7
A study of the epoxidation of 6-deoxyhex-5-enopyranosides. 1,5-Dicarbonyl derivatives and novel synthetic routes to D-xylo-hexos-5-ulose and D-lyxo-hexos-5-ulose.6-脱氧己-5-烯吡喃糖苷的环氧化研究。1,5-二羰基衍生物以及合成D-木糖型己糖-5-酮糖和D-来苏糖型己糖-5-酮糖的新合成路线。
J Org Chem. 2002 May 31;67(11):3733-41. doi: 10.1021/jo016378c.
8
The total synthesis of C-glycosides with completely resolved seven-carbon backbone polyol stereochemistry: stereochemical correlations and access to L-configured and other rare carbohydrates.
Chemistry. 2001 Nov 19;7(22):4771-89. doi: 10.1002/1521-3765(20011119)7:22<4771::aid-chem4771>3.0.co;2-j.
9
A highly stereoselective construction of beta-glycosyl linkages by reductive cleavage of cyclic sugar ortho esters.通过环状糖原酸酯的还原裂解实现β-糖基键的高度立体选择性构建。
J Org Chem. 2000 Dec 1;65(24):8171-9. doi: 10.1021/jo0005870.
10
Synthesis of new 2-phosphono-alpha-D-glycoside derivatives by stereoselective oxa-Michael addition to a D-galacto derived enone.通过对D-半乳糖衍生的烯酮进行立体选择性氧杂-Michael加成反应合成新型2-膦酰基-α-D-糖苷衍生物。
Carbohydr Res. 2008 May 19;343(7):1133-41. doi: 10.1016/j.carres.2008.03.009. Epub 2008 Mar 13.